Postoperative Cardiac Surgery Outcomes in a Statin-Native Population

Background Statin utilization had been associated with improved survival after cardiac surgery. We aim to study whether perioperative treatment with statin could be associated with increased postoperative complications. Design This was a retrospective, descriptive, single-center study. Settings We analyzed morbidity after cardiac surgery as well as the outcome related to statin therapy in a tertiary cardiac center. Patients A total of 202 consecutive patients were enrolled over 1 year after cardiac surgery. Intervention Patients were divided into two groups; Group I - statin users and Group II - nonusers. Measurements Measurements were baseline and follow-up laboratory markers for muscular injury including cardiac muscle and hepatic injuries and renal injuries. Results The incidence of rhabdomyolysis and elevation of liver enzymes did not differ between both groups. Postoperative atrial fibrillation was significantly lower in the statin group (P = 0.02). In addition, peak cardiac troponin and creatine kinase-MB did not differ significantly in the statin group. Statin-treated group had significant lower length of mechanical ventilation, and length of stay in the Intensive Care Unit and hospital (P = 0.036, 0.04, and 0.027, respectively). Conclusions Therapy with statin before cardiac surgeries was not associated with high incidence of adverse events.